Does Fish Oil Supplements Cause Gout
What is Uric acid?
Approximately 70% of gout patients have an overproduction of uric acid, the remaining 30% of gout patients have a poor elimination of uric acid, therefore it makes sense to eat fewer foods which help to produce uric acid, and improve uric acid elimination by way of the kidneys.
Uric acid is a by-product of the breakdown of certain foods in the body, and gout was once considered to be closely related just to diet. It is now understood that inheriting a problem with uric acid excretion from the body is probably one of the most common reasons for gout to occur. Improving a persons kidney function as much as possible has helped many gout sufferers I have seen over the years.
Uric acid is the end product of the metabolism of chemicals called purine that are found in many foods. Purines are also found naturally in the body, and normally, the body disposes of excess uric acid via the urine, but in people with gout uric acid accumulates in the body. This can be due to reduced excretion of uric acid by the kidneys or to overproduction of uric acid by the body. This accumulation of uric acid may also cause kidney stones, and it doesnt take a rocket scientist to work out that you need to improve the kidney function as much as is possible to help the patient overcome gout.
But No Benefit Seen With Fish Oil Sans Fish
Consumption of omega-3 polyunsaturated fatty acids , which are contained in fatty fish such as salmon, mackerel, and sardines, was associated with a significant decrease in the risk of gout flares, a large online survey found.
Among patients with gout, consuming any quantity of fatty fish in the previous 48 hours lowered the risk of an acute gout attack by 33%, with an adjusted odds ratio of 0.77 , according to Tuhina Neogi, MD, PhD, of Boston University School of Medicine, and colleagues.
However, risk was not lowered with use of dietary supplements such as fish oil in the previous 48 hours, with an adjusted odds ratio of 1.01 , the researchers reported online in Arthritis & Rheumatology.
That discrepancy may be explained by the fact that the usual levels of the biologically active n-3 PUFAs eicosapentaenoic acid and docosahexaenoic acid , found in commercially available supplements, are “far below that which is required for significant anti-inflammatory effect,” they observed.
Despite the availability of effective treatments for gout, flares of the disease remain common, and additional approaches to prevention and treatment are clearly needed.
In contrast, n-6 PUFAs such as linoleic acid and arachidonic acid, which are found in vegetable oils and other animal products, exert pro-inflammatory effects, and the ratio of n-3 to n-6 PUFAs is believed to be critical in triggering inflammation.
The study was funded by the National Institutes of Health.
Ignore These Side Effects At Your Peril
All these considered, what if there was a natural product that could help control gout symptoms? Well, there is krill oil.
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Fact : Fish Oil Can Be Consumed In Pill Form Or Through Cold Water Fish
Feeling ready to add fish to your diet? Consider adding it to your diet in pill form, or even prepare some fish dishes.
Head to your local grocery or drug store and pick up fish oil supplements derived from real fish. Supplements should contain both DHA and EPA as opposed to pesticides, PCBs, or traces of mercury. Be sure the amount of fish oil per capsule is less than three grams.
To get your fill by adding more fish to your diet, choose cold water fish dishes. Explore salt-water fish and wild-caught fish. Some popular and tasty types of cold-water fish include:
Be sure to talk to your medical care providers to learn about safe additions to your diet. Certain groups of people, such as pregnant women, should limit their consumption of certain types of fish. Specifically, pregnant women should avoid consuming swordfish, king mackerel, and tilefish, while limiting their consumption of albacore tuna to no more than eight ounces per month.
If you have joint pain that will not subside with natural remedies or over-the-counter medications, it may be a sign of a more serious condition. Visit the orthopaedic specialists at UPMC online or call 1-877-471-0935 to schedule an appointment.
Expert Q& a: Fish Oil Supplements With Gout
Find out what you should know about fish oil supplements if you have gout.
Question: A doctor advised me to take fish oil supplements to improve my cholesterol level. But the source of fish oil in many preparations includes sardines, trout and herring fish that are high in purines and on the list of foods I should avoid because I have gout. How much purine is in fish oil supplements? Should I take them or not?
Answer: Purines are found in the meat of the fish but not in highly purified, molecularly distilled fish oil, so it should not affect your gout. I recommend everyone consume at least 2,000 milligrams per day of EPA and DHA . Those with autoimmune disorders and arthritis should consume 3,000 to 6,000 mg in divided doses with meals.
Buy only pharmaceutical-grade, molecularly distilled fish oil supplements. And go to the supplement companys Web site and make sure you research what youre getting. Also, know that using fish oil supplements to bring down your cholesterol level may thin your blood. If you have any bleeding disorders or already are taking medications to thin your blood, such as clopidogrel or warfarin , please talk to your doctor.
James McKoy, MD Kaiser Permanente Moanalua Medical CenterMoanalua, Hawaii
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Potential Health Benefits Of Fish Oil
Research has found that regular fish consumption reduces the risk of death from all causes. Several potential health benefits of fish oil supplements are:
Multiple studies have confirmed that eating fish can help prevent coronary heart disease. The more fish in your diet, the lower the risk of death from heart disease and stroke. One study found that subjects treated with fish oil supplements after experiencing a heart attack had a 29% reduction in fatal cardiac arrhythmias.
Improved Cognitive Function
The DHA found in fish oil supplements has been proven to protect against Alzheimerâs disease and dementia. Researchers have also concluded that increased DHA consumption reduces the risks of diseases that often accompany Alzheimerâs, like diabetes and cardiovascular disease.
Alleviation of Rheumatoid Arthritis
Epidemiological studies suggest that omega-3 fatty acids prevent rheumatoid arthritis. One study found that these fatty acids control joint swelling, and itâs believed that they also help to alleviate autoimmune inflammation, the cause of rheumatoid arthritis.
What Is The Fastest Way To Get Rid Of Gout
What Is the Fastest Way to Get Rid of Gout? Nonsteroidal anti-inflammatory drugs : These can quickly relieve the pain and swelling of an acute gout episode. Corticosteroids: These drugs can be taken by mouth or injected into an inflamed joint to quickly relieve the pain and swelling of an acute attack.
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What Happens If You Take Fish Oil Everyday
When taken by mouth: Fish oil is likely safe for most people in doses of 3 grams or less daily. Taking more than 3 grams daily might increase the chance of bleeding. Fish oil side effects include heartburn, loose stools, and nosebleeds. Taking fish oil supplements with meals or freezing them can reduce these issues.
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Gout is arthritis
Gout is regarded as a form of rheumatism and is one of the most painful forms of arthritis. There are different types of arthritis such as osteoarthritis, the wear and tear arthritis of the larger joints like hips, knees, back, etc. Then there is rheumatoid arthritis which is the inflammatory arthritis affecting the smaller joints generally like the writs, fingers, etc. And then there is gout, what I call the red-blooded males arthritis. I can remember reading a book awhile ago about the era of the large ocean going vessels such as the Endeavour during the golden age of discovery. Many officers on board such vessels suffered terribly from gout. Mind you, they were the commanding men who drank plenty of rum and ate plenty of beef with lashings of gravy. So what has changed? Blokes still like to command, drink rum and coke or cold beer, and eat hot steaks and what red-blooded guy doesnt? I have never seen a committed vegetarian suffering with gout, and very much doubt they even exist in this country.
Signs and Symptoms of Gout Does Fish Oil Supplements Cause Gout
· Gout afflicts approximately up to 0.5% of the population of the western world.
· Over 95% of gout sufferers are men aged 30 or over.
· Gout is twenty times more likely in males than women.
· Gout is strongly associated with being overweight and having high blood pressure.
· Gout can also occur in women, more commonly after menopause.Does Fish Oil Supplements Cause Gout
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Ground Flaxseed As Part Of A Healthy Drink
When establishing a normal exercise routine many people often make the mistake of adding whey powder to their drinks.
One well kept secret is that frequent consumption of whey actually leads to hindering conditions like gout. Instead replace the whey with ground flaxseed by stirring 1 tablespoon of flaxseed into drinks like smoothies.
Alternatively you can add flaxseed into foods like oatmeal and cereal as well.
Lower Ldl Levels Are Better
In a JAMA editorial accompanying the study, Christopher P. Cannon, MD, of Brigham and Womens Hospital and Harvard Medical School wrote that aggressive LDL lowering is the ideal lower is better.
The JAMA studys findings echo those of another large 4,162-patient study, published in the New England Journal of Medicine. It concluded that LDL cholesterol levels of 62 were even better than levels of 95 at preventing death, heart attacks, and other cardiovascular-related problems in people with heart disease.
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Fish Oil And Arthritis
Some types of arthritis involve inflammation in the body, which can be eased by the omega-3 fatty acids in fish oil. Studies have shown that the fatty acids in fish oil can partially inhibit a number of aspects of inflammation.
The body doesnt naturally produce omega-3 fatty acids, so this nutrient must be obtained through diet and/or supplements. The main fatty acids that are known to help with inflammation are EPA and DHA, which can be obtained by eating fatty fish like salmon, anchovies, and tuna.
Conventional Medicines For Gout Have A Potential For Side Effects
The question of safety arises once again for pharmaceuticals, that are designed to cure, but also cause great harm.
- NSAIDs (Non-steroidal anti-inflammatory drugs
We discussed the limitations of some of these conventional medicines in our article about krill oil and arthritis, where we talked about the upside of NSAIDs such as aspirin and ibuprofen . With any inflammation, the usual course of action is reaching for a tub of pills, without thinking too much of the side effects.
Aspirin and ibuprofen both can cause stomach upsets, and used long term offer an array of side effects that make taking them, more of a problem than the reason you first took them like stomach ulcers and bleeding in the stomach.
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Which Drugs Raise Uric Acid Levels
Complementary And Alternative Therapies
A combination of therapies can be very effective at reducing both the length and frequency of attacks. When choosing complementary and alternative therapies for gout treatment, it is best to work with a knowledgeable provider. Herbs and supplements that may be beneficial for some people, may be harmful for others. If you are pregnant, or thinking about becoming pregnant, do not use any CAM therapies unless directed to do so by your physician.
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Are There Any Side Effects
Fish oil is usually well tolerated. A possible side effect from fish oil supplements is a mildly upset stomach . There is currently no evidence that fish oils increase the risk of bleeding or interact with medicines that affect bleeding, such as aspirin or warfarin. Despite this, it is recommended that you consult with your doctor before having major surgery or if you are commencing fish oil while taking warfarin. INR monitoring tests may be done more often at first, as with the addition of any new treatment, to ensure there are no side effects. If there is any bleeding, stop taking fish oils and consult with your doctor.
Cod Liver Oil Or Fish Oil
Fish oil is different from cod liver oil.
Cod liver oil contains oil from pressed cod livers only. It contains higher quantities of vitamins A and D than fish oil. The body needs these vitamins, but they can be harmful if people consume them in large quantities.
People who take fish oil or cod liver oil for arthritis will need to consume large amounts in order to obtain the benefits.
For this reason, fish oil is a more healthful source of omega-3s than cod liver oil, as people can consume large quantities without taking in too much vitamin A and D.
Rather than taking fish oil supplements, a person may prefer to include plenty of fish in their diet.
Good sources of omega-3s include:
According to the Arthritis Foundation, eating 36 ounces of a variety of fish above between two and four times a week helps reduce inflammation and protect the heart.
When buying fish, consider the following points:
- Is the fish likely to contain a high level of mercury? Check here.
- Is it from a sustainable source? Check here.
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How Can I Check My Uric Acid Levels At Home
A uric acid test measures the amount of uric acid in the body. Uric acid is a chemical thats produced when your body breaks down purines.How is a uric acid urine test performed? On day 1, urinate into the toilet after waking up. After that, take note of the time and collect all urine for the remaining 24 hours.
Fish That Are Ok To Eat
Fish and seafood that are OK to eat when you have gout are those in the “low-purine category,” meaning they have less than 100 milligrams of total purines per 100-gram serving.
The best options include Japanese eel, monkfish meat, and sablefish. The purine content of catfish, flounder, red snapper, salmon, sole, and tilapia skew slightly higher but are good options, too.
These fish are typically served boiled, fried, steamed, or baked.
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Scientific Support For Flaxseed
Flaxseed and gout are more linked than what many may think, according to various scientific studies.
One study conducted by Dr. Floyd Pacheco Jr., a podiatrist based in Albuquerque, New Mexico, and colleagues featured the comparison between flaxseed oil to soybean oil and to no supplementation at all.
The amount of uric acid found in the group of rats that consumed flaxseed oil was 34% less than the group that took no supplements, and 44% less than the soybean oil group.
Dr. Monika Styrczewska and a group of colleagues discovered in 2012 that a couple compounds of flaxseed share similarities to that of cannabidiol, or CBD.
The UV spectra and the retention time in UPLC analysis are the similar compounds.
This discovered compound, called a terpenoid, affects the gene expression in inflammatory processes in mice and humans and the CBD elements likely activate the cannabinoid receptor 2 gene expression.
Whole flaxseed, flaxseed oil and lignans were all put to the test in a meta-analysis on how much they could impact a persons LDL cholesterol levels.
A total of 28 studies were conducted from 1990 to 2008, and results included a reduction of total and LDL cholesterol by 0.08 and 0.10 mmol/L respectively.
In 1952 German chemist Dr. Johanna Budwig was the senior expert for fats and pharmacuetical drugs for the central government.
Budwig discovered that when they have been chemically treated the key qualities of unsaturated fats are destroyed.
Can Fish Oil Cause Gout Attack
Highly purified and molecularly distilled fish oil is not rich in purines. From this point of view, fish oil will not affect your issues in fact, it will help against the production of uric acid, so it is actually recommended.
You can have fish oil in a few different ways. You can get it by eating fish, which is contraindicated. The benefits will not outweigh the potential reactions. Then, you can also buy fish oil supplements, as chances are you do not have the tools and education to extract pure fish oil from fish. Focus on DHA and EPA two fatty acids in fish oil.
Healthy people should have more than two grams of these fatty acids on a daily basis. On the other hand, those with gout, arthritis or autoimmune issues should have three to six grams. You do not need to get everything in one go. Instead, divide the amount over the three main meals of the day or throw some oil in your salads.
To properly define the connection between fish oil and gout, make sure you invest in pharmaceutical grade supplements. You need to know what you are getting. Also, you should know that fish oil will reduce the cholesterol, which will thin your blood. If you have bleeding problems, talk to your doctor first.
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