Tuesday, September 27, 2022

Does Gout Run In Families

Time To Call The Doctor

Gout | Treating Severe Joint Pain | What Patients Should Know

A gout attack will usually go away in about 3 to 10 days. But you can feel better sooner if you treat it. To be sure that you have gout, see your doctor. Theyâll examine you, and they might do some tests.

These test help your doctor know if you have gout, or something else with similar symptoms:

  • Joint fluid test. Fluid is taken from the painful joint with a needle. The fluid is studied under a microscope to see if the crystals are there.
  • Blood test. A blood test can check the level of uric acid. A high level of uric acid doesnât always mean gout.
  • X-ray. Images of the joints will help rule out other problems.
  • Ultrasound. This painless test uses sound waves to look for areas of uric acid deposits.

Treating Gout And Diabetes

Patients need to know that both are chronic diseases treatable but not curable so they need to work with their health care providers to ensure they are treating both, says Dr. Bose.

Most patients with gout need to be on a medication that lowers their uric acid levels. And type 2 diabetes management depends on ideal control of body mass through diet and exercise as well as medical management of glucose levels, says Dr. Edgerton.

For gout, that means uric acid-lowering medication like allopurinol or febuxostat. People with type 2 diabetes either take medications to lower their blood sugar levels or to increase insulin production . And its safe to take medications for both conditions, says Dr. Edgerton.

What might get trickier is following exercise and diet recommendations. To improve blood sugar, you need to be more active, but if you have a gout flare or arthritis, that can be tough, says Dr. Edgerton. And a gout-friendly diet doesnt totally overlap with a diabetes-friendly one, he adds.

For example, you might have someone with diabetes being encouraged to kind of do a low-carb or a keto-centric diet. Well, thats not necessarily going to help with the gout, especially if its a high protein diet, which can be more difficult for gout patients.

How Is Gout Treated

Gout is normally treated with anti-inflammatory medication. If the condition lasts longer than a few days, you may then have to have steroids either in tablet form or as an injection.

The NHS have also recommended the following self-help too:

  • Take any medicine you have been prescribed as soon as possible it should start to work within 3 days
  • rest and raise the limb
  • keep the joint cool apply an ice pack, or a bag of frozen peas wrapped in a towel, for up to 20 minutes at a time
  • drink lots of water
  • try to keep bedclothes off the affected joint at night

For more information about Gout and the things you can do to avoid reoccurring attacks of Gout, please follow the link below:

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New Evidence That Gout Strongly Runs In Family

Date:
University of Nottingham
Summary:
Its historically known as the king of diseases and the disease of kings and was long thought to be caused by an overindulgent lifestyle, but now scientists have confirmed that gout strongly runs in families.

It’s historically known as ‘the king of diseases and the disease of kings’ and was long thought to be caused by an overindulgent lifestyle, but now scientists at The University of Nottingham have confirmed that ‘gout’ strongly runs in families.

Researchers in the Division of Rheumatology, Orthopaedics and Dermatology studied the whole population of Taiwan where gout is most prevalent in the world. The findings have just been published in the rheumatology journal, Annals of the Rheumatic Diseases.

Gout is a kind of inflammatory arthritis, with sudden onset of acute pain, redness and swelling in peripheral joints, most commonly the joint in the big toe. It is caused by the deposition of monosodium urate crystals, which is related to high uric acid in the blood. The resulting acute arthritis and lumps around the joint cause disability due to pain and loss of joint function.

There is also increasing evidence that gout is not only a disease of joints but also is associated with major cardiovascular and renal diseases .

Story Source:

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Gout: Symptoms, Causes and Natural Support Strategies

Some clients simply want to shed their excess weight to look better,however others tell us that health is the main reason. Does obesity run in families? Many of our past clients have successfully reversed medical conditions such as insulin resistance, diabetes, high blood pressure, and fatty liver disease, whereas others have managed to avoid having knee, or hip replacement surgery.You can read a Blog post on Vogue Magazine also featured Martin and Marions work.

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Why Do Individuals Develop High Uric Acid Levels

The major reason people develop gout is because their kidneys have difficulty excreting uric acid. This happens in 80% of cases of gout. Over-production of uric acid occurs in some patients due to inherited . In patients prone to gout, eating meat, liver, shellfish, and drinking beer can lead to gout attacks. However, kidney disease in the primary reason most people have gout.

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Gout In Children And Teens

If a child or teenager has gout, it is important that blood and urine tests be done to determine why gout has occurred. It is usually a sign of an underlying problem that is often easily treated.

In children, the first test to do if gout is suspected is to measure the blood uric acid level. If this is elevated , this could be a sign that gout is present. Other important procedures are for a doctor to insert a needle into the affected joint, withdraw fluid, and examine this fluid for uric acid crystals.

Causes of gout in children and teenagers include:

  • Inherited conditions that cause over-production of uric acid. These include HPRT deficiency and PRPP synthetase overactivity. These disorders are uncommon but are easily tested for. Patients produce extra uric acid and can have gout and kidney stones containing uric acid. These conditions usually occur in boys but can occasionally happen in girls as well.
  • Kidney diseases resulting in decreased ability of the body to get rid of uric acid. These can include:

– The most common type is due to mutations in the gene that produces a protein called uromodulin. In this condition, patients develop gout in their teenage years and have slow worsening of kidney failure over time. There are usually many other family members who have had gout or kidney disease.

– Any type of kidney disease can also cause gout in childhood.

We Live In An Obesogenic Environment

7 NATURAL Remedies That PREVENT Gout ð?

So why is the problem getting worse? The UKs National Institute for Health and Care Excellence , states that the almost non-stop global increase in obesity over recent decades is at least partly due to obesogenic environments.What does that mean exactly? Well, an obesogenic environment is basically one where there is an unlimited supply of high-calorie, energy-dense foods, whilst at the same time providing limited opportunities for physical activity. Its the exact opposite environment to what our hunter gatherer ancestors experienced.

Does Obesity Run in Familiesand Obesogenic Environments

Research shows that the number of takeaways in a particular area has a direct impact on the level of obesity of the population. A Cambridge study, found that those who live, or work, near clusters of takeaway outlets, are twice as likely to be obese, compared to those who are not as exposed to such temptations.

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Positive Lifestyle Changes To Prevent Gout

Gout can come back if your uric acid levels remain high or rise again in the future.

You can reduce your risk of developing gout again by making positive lifestyle changes and sticking to them. These include:

  • Eating a well-balanced diet a GP might advise certain foods to avoid

  • Working towards maintaining a healthy weight, but without using crash diets

  • Going alcohol-free for a few days each week

  • Staying well hydrated

  • Getting regular exercise low impact activities like walking and swimming are ideal

  • Stopping smoking

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How Do You Get Gout

So, how do you get gout after all? Having lots of beer and purine rich foods might be the most popular issue. But then, there are people who never bother about what they eat or drink and they never experience gout. This is because there are a few risk factors to take in consideration and each of them could increase the risk of developing the affection.

Managing Gout And Diabetes

7 Risk Factors of Gout

Dr. Edgerton says he always informs his gout patients about the link between gout and diabetes. Theyre both lifestyle-influenced conditions, meaning the changes that have to be made have to be incorporated into a daily activity. Its not as easy as just taking a pill for either disease, he notes.

So besides being diligent about getting medical care and following a treatment plan from your primary care doctor and other specialists , heres what else may help:

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As Tv Screens Get Bigger So Do Our Backsides

Is it just coincidence that as our widescreen TVs increase in size we are also becoming broader in the beam? Generally, as a species we spend less and less time moving around, and we are expending very little energy. So, nowadays, instead of doing any physical activity, having a night in on the sofa and binge-watching our way through a whole series, is a very regular weekend activity. Most modern gadgets, such as remote controls, voice activated devices, power steering in cars, suitcases on wheels, and travelators in airports are all specifically designed to save us work. Our hunter gatherer ancestors would be horrified!

Consequently, the obesity epidemic can be considered a collective, a combined response to this ever-worsening environment. Also, as we know, obesity is an ever-growing public health problem. It has resulted in the increased risk of developing diabetes, heart disease and stroke. Further information from

How your genetics control energy balance

The brain, not your stomach, regulates food intake, byrespondingto incoming signals. These signals are transmitted by hormonessuch as leptin, insulin, and ghrelinand other small molecules. Using the signals from the hormones, the brain responds with instructions to the body. This can be either to eat more, move less, or eat less and move more. Genes you were born with are the basis for the signals and responses that guide food intake, and very small changes in these genes can affect their levels of activity.

Family Exposure And Risk Of Gout

The risk of gout was significantly higher in individuals with affected first-degree relatives than in the general population, the RRs being 1.91 in men and 1.97 in women . Individuals with affected second-degree relatives also had an increased risk of gout, albeit significantly lower than those with affected first-degree relatives, with RRs of 1.27 in men and 1.40 in women. Figure 2 shows that individuals with an affected twin had the highest risk, followed by individuals with an affected sibling, then individuals with an affected offspring and, finally, individuals with an affected parent. Same-sex twins had the highest RR, being higher in female-female twin pairs than male-male twin pairs. The RRs for gout in individuals with any category of affected second-degree relative were lower than RRs in those with affected first-degree relatives . The RRs also increased with the number of affected first-degree relatives. Compared with the general population, individuals with one, two or three or more categories of affected first-degree relatives had RRs of 1.87 , 3.22 and 4.96 , respectively. This trend was more prominent in women .

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Tip No 5 Stay Away From Sugar And Highly Processed Foods

Its a fact that sugar and highly processed foods have addictive properties!So much so, that many people find that once they start eating these foods, they literally cant stop. And, of course, if youre making such poor food choices, this in turn will make it almost impossible for you to lose weight. So, our advice is to choose healthy, unprocessed foods and limit the amount of sugar you consume. As a result, you will have far more control over how much you eat and also how much weight you can lose.

What Happens At Your Appointment

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The GP may ask about your diet and if you drink alcohol.

They may refer you to see a specialist and arrange a blood test and scan. Sometimes a thin needle is used to take a sample of fluid from inside the affected joint, to test it.

The blood test will find out how much of a chemical called uric acid there is in your blood.

Having too much uric acid in your blood can lead to crystals forming around your joints, which causes pain.

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Gout Symptoms And Complications

Gout is not gout until symptoms occur. When they do, they usually come on suddenly and, at least initially, affect a single joint. Within hours, that joint becomes red, swollen, hot, and painful they’re called gout attacks for a reason. It’s easy to mistake a gout attack for a localized infection of a joint. The metatarsophalangeal joint at the base of the big toe is often the site of the first attack, but the knees, ankles, and joints between the many small bones that form the foot are also common sites. People who already have osteoarthritis the most common form of arthritis often experience their gout attacks in the joints of the finger

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Tip No 3 Drink A Glass Or Two Of Water Before Your Meal

Reduce Your Calorie Intake by over 20%, with almost with no effort! Research results, published by Harvard Medical showed that people who drank two large glasses of water, just before eating, consumed, on average, around 20% less food than previously. This is possibly as a result of the stretching and fullness sensation in the stomach.

Treating A Gout Attack

What Is Gout? Causes, Symptoms, And Treatment ...

As is true for many painful conditions, the first-line treatment for a gout attack is taking one of the nonsteroidal anti-inflammatory drugs , such as diclofenac, ibuprofen, or indomethacin. For people who can’t take NSAIDs, a drug called colchicine is an alternative. It’s been used for centuries maybe even longer specifically for gout. The trouble with colchicine is its side effects, especially the copious diarrhea. If neither an NSAID nor colchicine is an option, then gout attacks can be treated with an oral corticosteroid, such as prednisone, or with corticosteroid injections into the joints.

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Who Does Gout Affect

Others most affected by gout include people with kidney disease. Gout is also strongly linked to obesity, hypertension , hyperlipidemia and diabetes. Because of genetic factors, gout tends to run in some families. Gout rarely affects children, but pediatric gout is possible.

There are a number of risk factors for gout.

The more risk factors a person has, the greater the risk for developing gout.

Study Population And Classification

The study population consisted of all NHI beneficiaries in 2004, representing 99.8% of the total population of Taiwan at the end of 2004.38 Enrolled individuals were classified according to the affection status of gout of their first-degree and second-degree relatives who were registered in the NHI before 2004.

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Gout Runs In The Family

    A population-based study confirms that gout aggregates within families, according to a report in Annals of the Rheumatic Diseases.

    Gout is the most common inflammatory joint disease. High heritability of hyperuricemiathe main driver of urate crystal deposition and the development of gouthas led to efforts to identify susceptibility genes, explained a research team led by Chang-Fu Kuo, MD, of the University of Nottingham, Nottingham, U.K. Dr. Kuo and colleagues sought to examine familial clusters of gout and to estimate the heritability and environmental contributions to gout susceptibility in the general population in Taiwan. Taiwan has one of the highest reported estimates of gout prevalence worldwide.

    Kuos group evaluated information from 1,045,059 patients with physician-diagnosed gout, obtained from a national health research data base in Taiwan. Among subjects with a first-degree relative with gout, the risk for developing gout themselves was approximately twice that seen in the general population. The risk increased with the number of first-degree relatives affected.

    Men and women whose second-degree relatives suffered from gout had a 27% and 40% increased risk of gout compared with the general population.

    The researchers noted that because the study was confined to Taiwan, studies of familial risk in other populations are needed to determine the generalizability of the findings to other populations.

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