Pain That Wakes You Up
More often than not, gout flare-ups happen in the middle of the night, interrupting a peaceful slumber with intense pain.
“It’s true, gout attacks are more common overnight,” Dr. Seligman says. But exactly why is a bit of mystery.
One theory: “It has been postulated that this relates to cooler body temperature at night,” she says.
The foot is cooler because it is the farthest body part away from the heart.
At cooler temperatures, uric acid turns into crystals and could settle into a cool spot like the foot and ankle.
Other theories center on sleep disorders that cause less oxygen in the blood, such as sleep apnea.
Gout Frequently Flares In Your Knee But You May Not Always Know That Your Knee Pain Is Due To Gout Heres How To Tell Since Prompt Treatment Can Reduce Your Risk Of Complications
Knee pain can be a common symptom of several types of arthritis, as well as many other conditions or injuries. If your knee stiffness is accompanied by a burning pain and is warm to touch, you may have a gout flare in the knee.
Though gout is most often associated with the big toe, gout tends to flare in areas that already have arthritis, says Robert Keenan, MD, a rheumatologist with Articularis Healthcare in Summerville, South Carolina. Although gout can strike in many different joints, as a general rule, gout works its way up the body. If its not treated, it works its way up from the big toe, through the ankle, to the knee, and then to the lower spine and so on.
Gout can affect both knees, but typically is felt more strongly in one knee say, where you may have arthritis wear-and-tear to begin with.
Learn more about what causes gout in the knee, as well as ways to treat the pain and prevent it in the future.
Effective Medical Treatment For Gout
The American College of Rheumatology released gout management guidelines in 2012 and updated them in 2020. They recommend drugs classified as urate-lowering therapy for those who have experienced two or more gout attacks in a year as well as for those with joint damage from gout.
Specifically, the organization recommends allopurinol as a first-line treatment for all gout patients, even those with chronic kidney disease. Next in line is febuxostat both are a class of drugs called xanthine oxidase inhibitors.
In addition, the guidelines recommend use of anti-inflammatory medications including NSAIDs, prednisone, or colchicine along with the other medication.
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Which Joints Are Involved In Gouty Arthritis And Why Is It Most Common In The Foot
As with all other known types of arthritis, Gout has particular joints it tends to attack, and the foot is its most common location. Gout especially favors the bunion joint, known as the first metatarsophalangeal joint , but the ankle, midfoot and knee are also common locations, as is the bursa that overlies the elbow.
The bunion joint is the first joint involved in 75% of patients and is ultimately involved in over 90% of those with this condition. . It is thought that this joint is especially involved in gout because it is the joint that receives the highest pounds per square inch of pressure when walking or running.
Late in gout, if untreated, multiple joints can be involved, including the fingers and wrists. The shoulder joint is very rarely involved by gout and the same is true of the hip.
Figure 5: Location of Gout Attacks
Treatment For Gout In The Heel

There is no cure for gout, but treatment to limit attacks and control painful symptoms are available.
If your doctor diagnoses gout, they will most likely suggest medication and certain lifestyle changes based on findings in the testing and your current health.
Certain medications treat gout attacks or flare-ups. Others reduce the risk of potential gout complications.
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Cartilage Damage And Osteoarthritis
More recently, the deposition of MSU and calcium pyrophosphate dihydrate crystals in areas of cartilage damage has been described in a cadaveric study which examined 7855 adult human tali from 4007 donors . Crystal deposits, both MSU and CPPD, were an uncommon finding, being present in specimens from only 5% of donors. However, where seen, crystal deposits were usually found within or adjacent to a cartilage lesion. Only 8% of tali with crystal deposits had no gross evidence of cartilage degeneration. Cartilage lesions tended to be located at sites of biomechanical stress such as the articulation of the margin of the trochlea with the tibia or fibula or where apposition with anterior tibial osteophytes was thought to have occurred. In a separate study, the epitaxial nucleation and growth of MSU crystals was observed to occur on fragments of articular cartilage . Thus there appears to be a relationship between cartilage lesions and the anatomical location of MSU crystal deposition.
Conservative Treatment For Gout Includes:
In order to prevent recurrent gouty attacks, oral medications such as Allopurinol, Colchicine, Uloric, and Probenecid can be used. The medication used to prevent gouty attacks is determined by whether or not the patient is overproducing or under excreting uric acid.
One of the mainstays of preventing recurrent gouty attacks is to follow a gout friendly diet. This includes limiting or avoiding beer, shellfish, and certain meats. Patients are instructed to learn about all of the foods that can cause gout and are instructed to avoid these foods.
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Gout In Ankle Treatment And Best Home Remedies
As the primary cause for gout in the ankle is the accumulation of uric acid crystals, the measure which helps to reduce the formation of uric acid crystals in the joints can only help in getting rid of ankle gout pain permanently and fast.
An important chemical that helps in reducing or controlling the uric acid levels in the blood is bromelain.
Bromelain supplements are therefore recommended by doctors for treating gout in the ankle and foot.
The chemical bromelain is also highly available in pineapple.
Hence consuming pineapple daily acts as one of the best home remedies for gout in the ankle.
This will gradually help in reducing the uric acid levels in the blood and thus leads to reducing the swelling and pain in the affected joints.
Fruits such as bananas are rich in fiber and contain low purines.
It also contains high levels of potassium that helps in converting uric acid crystals into liquid form .
Adding 1-2 bananas to your daily diet can, therefore, help a lot in managing the gout condition effectively at home naturally.
Apple cider vinegar for gout is also many times recommend by medical experts.
ACV benefits are unlimited and it can actually help manage lots of other health conditions .
You can, therefore, take this on a regular basis daily to cure your pain and inflammation.
Few other natural home remedies and ingredients that can provide immediate gout pain relief are:
- Ginger root
Gout Attack Vs Chronic Gout
It is possible to have a gout flare-up and never experience another. Repeated instances of acute gout are called chronic gout17.
The treatment goals for a gout attack are different than those for chronic gout. When treating a gout attack, the goal is to relieve pain and inflammation. When treating chronic gout, the goal is to prevent future gout attacks and long-term joint damage.
While some people with chronic gout may get frequent gout attacks, others may have years in between attacks. If chronic gout is not treated, attacks may become more frequent and/or last longer.
Left untreated, a gout attack will usually resolve itself within a few days or weeks. Chronic gout can permanently damage a joints tissues and decrease its range of motion. For this reason, it is important to recognize symptoms, understand risk factors, get an accurate diagnosis, and treat and prevent gout.
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What Are The Symptoms Of Gout
Gout typically only affects a singular joint at a time. Most patients will typically experience the symptoms of gout in their big toe however, some may also experience gout in their ankles, knees, and many of the joints of the feet.
The onset of gout flares is often immediate, and for many patients, symptoms can last days or even weeks. Most will experience symptoms at night or early in the morning. The remission period between flare-ups can be longmonths or years for someand depends on a patient’s ability to effectively manage and treat the disease.
The common symptoms of gout include:
- extreme pain in the affected joint
- swelling
- redness
- joint often feels hot to the touch
As gout more often than not affects joints in the feet, patients may find it difficult to put weight on their feet for the duration of their flareup. For some patients, the continuous buildup of uric acid crystals in affected feet joints can result in the formation of tophi, lumps under the skin. If left untreated can lead to the erosion of bone and cartilage.
What Causes Ankle Gout
Gout occurs due to the accumulation of urate crystals in the joint, causing inflammation and intense pain. These crystals can form when you have high uric acid in the blood . Your body innately produces uric acid when it breaks down purines-substances that are found naturally in the body, as well as in certain foods, such as steak, organ meats, and seafood. Other foods that promote higher levels of uric acid include alcoholic beverages and drinks sweetened with fructose .
In a normal individual without gout, uric acid dissolves in the blood and passes through the kidneys to be expelled in the urine. But sometimes, the body produces too much uric acid, or the kidneys excrete too little of it. When this happens, uric acid can build up, forming sharp, needle-like urate crystals that become deposited in a joint or surrounding tissue causing pain, inflammation, and swelling.
Uric acid crystals tend to form in cooler temperatures, which is why they tend to form in the distal extremities, such as the hands and feet, which have a higher likelihood of becoming colder than the rest of the body.
Possible medical and health triggers of gout include:
- Infection
- Intense pain
- Possible fever
Symptoms tend to recur anywhere from six months to two years after the initial episode, with approximately 60 percent of gout patients having a recurrence within one year.
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Gout In Arm And Elbow: Can Gout Affect Your Elbow And Arm
The elbow is formed by three bones out of which two bones belong to the forearm and known as the radius and ulna. The third bone, which is also the largest and the only bone in the upper arm, is called the humerus. It is important because it helps in lifting, throwing and writing. Uric acid crystals will typically deposit in the middle section where are all three bones connect in the joint capsule of the elbow.
A gout attack in your elbow will also happen unexpectedly. You will wake up in the morning to find that your elbow is suddenly swollen and painful. You will experience severe pain and tenderness, just like the big toe, your elbow will be extremely sensitive to any pressure even to a bed sheet.
Your elbow will have red and swollen appearance as if its puffed up and you may feel warm. Your arm mobility will be limited. Due to the redness, the skin on your elbow may be peeling and flaking. You may feel itchy as well due to gout in elbow and arm.
Treating Gout With Medications

Certain medications reduce the pain and inflammation of gout attacks, such as anti-inflammatory drugs , colchicine, and corticosteroids. Other medications decrease the level of uric acid in the blood and prevent the deposit of uric acid in joints , the kidneys , and in tissue , helping to prevent further attacks and complications. These drugs include allopurinol, febuxostat, lesinurad, and probenicid.
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Symptoms Of Gout In Wrist
Gout in wrist joint is not as common as it is in big toe and ankle. Therefore sometimes even for the physician it is difficult to diagnose. The presenting symptoms of gout in wrist are sudden and severe pain in wrist joint. Usually gout in wrist is unilateral. It means only one wrist is affected at a time. However, sometimes both the wrists are involved.
Excruciating pain makes the patient restless and irritable. Although gout is more common in men, it has been seen that gout in worst affects both the genders equally. Soon swelling and redness develops in the wrist area. The joint is tender to touch. Sometimes even draught of air hurts the patient. With swelling and pain, the patient is unable to work with the affected hand.
Wrist movements are restricted due to swelling and pain. In chronic cases there may be irreversible damage to the wrist joint. Gouty tophi may form under the skin area of wrist. Usually pain and swelling lasts for few days or weeks and gradually reduces until the next attack.
Gout In Ankle: Causes Symptoms Treatment And Prevention
Written byEmily LunardoPublished onNovember 10, 2017
Gout in the ankle or ankle gout is an inflammatory condition of the joint leading to swelling, pain, and redness of the ankle. Gout is a complex form of arthritis that can affect anyone, with over eight million Americans suffering from the condition today. Men are typically affected more, but postmenopausal women become increasingly susceptible in their later years.
The most common joint affected by gout is the big toe, but joint pain may also be experienced in the knees, hands, ankles, and wrists. Having gout in the ankle can be very debilitating as it encumbers your ability to walk normally.
This article will answer the question what causes gout in the ankle, giving you a better understanding of the intricacies of the condition to better treat it.
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How To Treat Gout In The Ankle
The following are various remedies for gout in the ankle. By addressing gout in ankle symptoms before they get out of control, it can help mitigate pain and swelling. It is recommended to speak to your doctor about particular distressing pain caused by gout as they can provide better-tailored gout ankle treatment.
Risk Factors And Potential Causes Of Gout
Gout strikes men more often than women until women undergo menopause, and then women experience increased risk. Being overweight or obese, having recent surgery, and experiencing a trauma also increase your risk, as well as your family history.
Your body produces uric acid when it breaks down purines a substance found naturally in your body, and also in high-protein red meat, organ meat, and certain types of seafood. In addition, alcoholic drinks, beer, and beverages sweetened with fructose can raise your natural uric acid levels. When your body either creates too much uric acid or excretes too little, it can lead to gout. Hundreds of years ago, gout was called the disease of kings because the average peasant couldnt afford such rich food and drink.
Medical conditions like untreated high blood pressure, diabetes, heart disease, and kidney disease can also increase your chances of developing gout, as does taking certain medications, such as thiazide diuretics and low-dose aspirin.
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How Is Gout Managed
Here’s the truth: there is no cure for gout, although there are many ways to treat it and prevent flare-ups.
Oddly enough, some people only have a gout flare-up once, while others have flare-ups more often.
So how might you avoid future flare-ups? It makes sense to avoid high-purine foods, but eating a purine-free diet is pretty hard to do.
And though elevated uric acids are a precursor to a gout attack, having high levels doesn’t mean you’ll automatically have an attack. Still, eating and drinking excessive amounts of high-purine foods isn’t good for anyone.
What Else Should I Ask My Healthcare Provider About Gout
Consider asking your healthcare provider:
- What is causing the gout?
- Do I have any joint damage?
- What can I do to prevent future attacks?
- Can any gout medications help me?
- How long will I need to take gout medications?
A note from Cleveland Clinic
Gout is a painful form of arthritis. Extra uric acid in your body creates sharp crystals in the joints, leading to swelling and extreme tenderness. Gout usually starts in the big toe but can affect other joints. Gout is a treatable condition, and the uric acid level can be decreased by medication and lifestyle changes. Talk to your healthcare provider about medications that can reduce uric acid levels. They can also discuss changes you can make to your diet and lifestyle to prevent and reduce gout attacks.
Last reviewed by a Cleveland Clinic medical professional on 11/15/2020.
References
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What Does A Gout Attack Look And Feel Like What Would A Foot Or Toe With Gout Look Like
When gout occurs, the joint tends to be extremely painful and is warm, red and swollen . The inflammation that is part of a gout attack is systemic, so that fever and chills, fatigue and malaise are not uncommonly part of the picture of a gout attack.
Figure 6: Toe with Acute Attack of Gout
Gout attacks can occur in joints that look normal, or in joints that have easily visible deposits of uric acid. These deposits are called tophi and can be in numerous locations, but especially on the feet and elbows. In Figure 9, the little finger of the right hand is bandaged since fluid was just removed from it, which demonstrated innumerable uric acid crystals.
Figure 7a: Tophi on Foot
Figure 7b: Tophus Over Achilles’ Tendon
Figure 8: Tophus on Elbow
Figure 9: Tophi on Hands
Figure 10: Large Tophus of Finger
While some gout attacks will solve quickly by themselves, the majority will go on for a week, several weeks, or even longer if not treated. Since gout attacks are usually quite painful and often make walking difficult, most gout sufferers will request specific treatment for their painful condition.