The Real Side Effects Of Coffee
Something to be aware of as you sip your Java!
De-sensitizes your body to caffeine We all know what happens when you drink coffee regularly: you have to drink more and more to get the same effects.
Caffeine is as addictive as nicotine and recreational drugs, and it affects your body the same, meaning no matter how much you drink, you never get the same high you got the first time.
The more coffee you drink, the more you need to drink to get that same effect. This is why so many coffee drinkers go from mild Americana-style coffee to cappuccinos and espressos. For espresso drinkers, there are few optionslike Death Wish Coffee
Not only is it hard to get the same high, but you develop a dependence on caffeine in addition to the tolerance. If you stop drinking coffee, you get the shakes, a headache, and other downsides.
Affects nutrient absorption One of the most notable examples is coffees effect on calcium absorption. Coffee essentially interferes with your bodys ability to absorb calcium, preventing it from reaching your bones.
Excessive caffeine intake can lead to bone thinning and osteoporosis.
Excess body fat Now, to be clear, this isnt a side effect of coffee, per se. Just drinking black coffee can actually stimulate weight loss, and will increase your energy at the gym.
Its a bit of a hard saying. To keep your coffee healthy, you have to keep it simple. However, this makes it bitter and harder to drink. Tough call, right?
Who Is Affected By Gout
Gout can affect anyone. It usually occurs earlier in men than women. It generally occurs after menopause in women. Men can be three times more likely than women to get it because they have higher levels of uric acid most of their lives. Women reach these uric acid levels after menopause.
People are more likely to get gout if they have:
- Obesity, or a lot of extra weight.
You are also more likely to develop gout if you:
- Consume a diet high in animal proteins
- Consume a significant amount of alcohol
- Are on water pills .
What Can Trigger A Gout Attack
Several things can cause the crystals to shake loose into your joint cavity, triggering an attack. These include:
- a knock or injury to the joint
- an illness that may make you feverish
- having an operation
- having an unusually large meal, especially a fatty meal
- drinking too much alcohol
- starting urate lowering therapy, especially at a high dose, or not taking your treatment regularly each day.
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What To Do During An Attack
- take any medication you’ve been prescribed as early as possible after you notice an attack this should start to have an effect within two or three days
- rest and raise the limb
- avoid knocking or damaging the affected joint
- keep the joint cool remove surrounding clothing and apply an ice pack, such as a bag of frozen peas wrapped in a towel
- ensure you’re well hydrated
Apply the ice pack to your joint for around 20 minutes. Don’t apply ice directly to your skin and don’t apply it for more than 20 minutes at a time because this could damage the skin.
If necessary, you can keep reapplying an ice pack to your skin during an attack, but you should wait until your skin has returned to a normal temperature first.
Medications For Acute Gout
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How Can I Manage My Gout And Improve My Quality Of Life
Gout affects many aspects of daily living, including work and leisure activities. Fortunately, there are many low-cost self-management strategies that are proven to improve the quality of life of people with gout.
For gout in particular:
- Eat a healthy diet. Avoid foods that may trigger a gout flare, including foods high in purines , and limit alcohol intake .
CDCs Arthritis Program recommends five self-management strategies for managing arthritis and its symptoms. These can help with gout as well.
Dietary Changes To Minimize Medicines
Although gout may be inevitable for some, dietary and lifestyle changes may reduce gout flare-ups and reduce the needs for drugs. Certain foods, such as red meat, some seafood and alcohol, are known to contain high levels of purines, substances in plant and animal food that your body converts to uric acid. Bhatt recommends a vegetarian, low-purine diet to decrease the likelihood of gout attacks. Low-purine foods include low-fat non-fat dairy products, vegetables, nuts and grains. He also recommends that patients maintain a healthy weight, as obesity is associated with gout.
The Gout & Uric Acid Education Society also recommends limiting intake of fruits that contain a high level of fructose, a naturally occuring sugar, as well as cutting back on soft drinks, which contain high-fructose corn syrup. Fruits high in fructose include apples, grapes, peaches and pears. In addition, you should avoid cereals, ice cream, candy and fast food, as they can be high in sugar and salt.
As part of the long-running Nurses Health Study, researchers looked at the relationship between coffee consumption and the risk of gout in nearly 90,000 women over the course of 26 years. It found a reduced risk for women who consumed coffee, according to a 2010 study published in the American Journal of Clinical Nutrition.
Edwards says drinking cherry juice can decrease gout flare-ups, but patients who need a uric acid medication need to stay with it for life.
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What Should I Know About Storage And Disposal Of This Medication
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture .
It is important to keep all medication out of sight and reach of children as many containers are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location â one that is up and away and out of their sight and reach.
Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA’s Safe Disposal of Medicines website for more information if you do not have access to a take-back program.
How Is Gout Treated
Gout can be effectively treated and managed with medical treatment and self-management strategies. Your health care provider may recommend a medical treatment plan to
- Manage the pain of a flare. Treatment for flares consists of nonsteroidal anti-inflammatory drugs like ibuprofen, steroids, and the anti-inflammatory drug colchicine.
- Prevent future flares. Making changes to your diet and lifestyle, such as losing weight, limiting alcohol, eating less purine-rich food , may help prevent future attacks. Changing or stopping medications associated with hyperuricemia may also help.
- Prevent tophi and kidney stones from forming as a result of chronic high levels of uric acid. Tophi are hard, uric acid deposits under the skin. For people with frequent acute flares or chronic gout, doctors may recommend preventive therapy to lower uric acid levels in the blood using drugs like allopurinol, febuxostat, and pegloticase.
In addition to medical treatment, you can manage your gout with self-management strategies. Self-management is what you do day to day to manage your condition and stay healthy, like making healthy lifestyle choices. The self-management strategies described below are proven to reduce pain and disability, so you can pursue the activities important to you.
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Important Information About All Medicines
This medicine is for you. Never give it to other people even if their condition appears to be the same as yours.
If you buy any medicines ‘over-the-counter’, always check with a pharmacist that they are suitable for you to take alongside your other medicines.
If you are having an operation or any dental treatment, tell the person carrying out the treatment which medicines you are taking.
Do not keep out-of-date or unwanted medicines. Take them to your local pharmacy which will dispose of them for you.
If you have any questions about this medicine ask your pharmacist.
Are Patients Being Overlooked
Dr. Fields says the back pain of an attack could be mistaken for something else and treated as such. But what the patient really needs is medication to lower their uric acid level.
Even though a doctor may know the patient has gout, they may assume the back pain is from a herniated disc or osteoarthritis, he explains. They have to do imaging or a biopsy to find the uric acid deposits in the spine.
Spinal gout is rare, but it may be worth talking to your doctor about if you have back pain and a history of gout. You should be even more suspicious if you use diuretics, have high blood pressure or are obese. Early diagnosis and treatment with uric acid-lowering drugs can prevent the need for surgical intervention.
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Could Your Back Pain Be Gout
If you have ever had back pain, you know how difficult it can be to pinpoint the cause. From bone spurs to overworked muscles to slipped discs, theres no shortage of ailments that could be at the root of your aching lumbar.
And heres one more. Over the last 10 years, rheumatologists have documented more cases of gout appearing in the spine. So if you are one of the 8 million Americans with this inflammatory form of arthritis and you have unexplained back or neck pain, tingling sensations down your arm or leg, or numbness theres a small chance the culprit could be your gout.
Getting The Most From Your Treatment
- Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress.
- Do not drink grapefruit juice while you are on colchicine. This is because grapefruit juice increases the risk that you will experience side-effects from the colchicine.
- Colchicine tablets are taken in short courses of treatment to relieve the pain of a gout attack. If you have frequent attacks of gout, let your doctor know as they may prescribe another medicine for you to take every day to help prevent the attacks from occurring.
- There are a number of lifestyle changes that you can make to help reduce the risk of having a gout attack. These include losing weight , eating a healthy diet and not drinking much alcohol or sugar-sweetened soft drinks. Your doctor will advise you about the changes which could benefit you.
- Never take more than the prescribed dose. Taking too much colchicine can cause serious problems. If you suspect that someone has taken an overdose of colchicine or has swallowed some by accident, you must contact a doctor straightaway. Alternatively, go to the accident and emergency department of a local hospital. Do not delay. Take the container with you, even if it is empty. This is so the doctor knows what has been taken.
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How To Take Colchicine
- Food and drink: Swallow your tablet whole with a full glass of water. Take it with food to reduce stomach upset. Avoid drinking alcohol as it can cause stomach problems. Do not drink grapefruit juice as it increases the risk of side effects.
- Other medicines: Tell your doctor or pharmacist about all other medicines you are taking. Colchicine can be harmful when taken with some other medicines, such as antibiotics and medicines for pain relief.
How To Prevent Gout Flare
In addition to taking specific medications, there are a few things you can do to prevent recurrent gout:
- Limit your intake of alcoholDiscuss with your doctor the appropriate amount of alcohol, if any, that is safe for you. Studies show that alcohol, especially beer, and sugary drinks link to an increase in gout symptoms, so try to limit consumption of these whenever possible.
- Maintain a healthy weightConsume healthy meal portions, exercise regularly, and avoid fasting or crash diets.
- Drink plenty of waterThe guideline is to drink at least eight glasses of water a day and limit your intake of beverages with high fructose levels.
- Limit your intake of meatEating high-purine foods, such as veal, venison, liver, fish, and scallops can increase your uric acid levels and lead to a gout attack.
- Eat more low-fat dairy foodsThese can be alternatives to some of the protein youre getting from meat.
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Are There Home Remedies For Gout
- Take medications as prescribed.
- While a joint is hot and swollen, use a cane or similar support to keep weight off that joint.
- It may be helpful to keep the swollen joint elevated above the chest as much as possible.
- Ice packs can be helpful in relieving pain and reducing inflammation.
- Maintain adequate hydration to minimize the frequency and intensity of attacks.
- Drink cherry juice to decrease the intensity and severity of attacks.
- Avoid eating red meats, internal organs, yeast, shellfish, and oily fish because these increase the risk for gout.
While some medications are used to treat the hot, swollen joint, other medications are used to prevent further attacks of gout. With any of these medications, call a doctor if you think they are not working or if you are having other problems with the medication.
Medicines used to treat acute gout and/or prevent further attacks are as follows:
Rabbit Infection Experiments Using Ligated Intestinal Loops
Animal experiments were approved by the IACUC of the Univ. at Buffalo. The 10-cm lengths of ileum were tied into segments as previously described and injected with uric acid alone, uricase alone, or both. Loop contents were collected after 20 h. Wild-type rabbit EPEC strain E22, serotype O103:H4, was used as the infecting strain in and has been previously described .
Formation of uric acid in vivo in rabbit intestinal loops in response to EPEC infection. Panel A. Uric acid levels were measured in the fluid that accumulates in the intestinal loops following infection with rabbit EPEC strain E22 at 20 h after infection, with and without 1 M EHNA, an adenosine deaminase inhibitor. Panel B, microscopic evidence for uric acid crystal formation in the unfiltered loop fluid of a rabbit infected with E22 with 35 U/mL ADA. The large group of birefringent crystals was 470 m in size in the vertical dimension. Panel C, pro-inflammatory effects of exogenous uric acid in vivo in rabbit intestinal loops. No pathogenic bacteria were added in the experiment shown in Panel C, but instead uric acid, uricase, or the combination of the two was added. Loop fluid was analyzed for MPO activity. Panel C is from Gut Microbes 4 5 14, 2013, , under the provisions of the Creative Commons Attribution License.
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