Data Sources And Search Methods
The search process was extended by perusing the reference section of all relevant studies and manually searching through the abstracts of key journals and papers published at major annual meetings. The search terms included the following: AND AND . We also checked the reference list of screening studies to identify other similar studies. The search strategy excluding manual search methods is shown in . This study was based on guidelines outlined in the Preferred Reporting Items for Systematic Reviews and Meta-Analyses .
Search strategy in PubMed up till August 15, 2019 .
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| 1 OR 2 OR 3 OR 4 |
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| 6 OR 7 OR 8 |
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Are There Any Side Effects Of Consuming Tart Cherry Juice
Too much of anything is bad. Overconsumption of tart cherry juice could cause diarrheabecause of the prevalence of high amounts of sorbitol a type of sugar alcohol and excessive fiber. Moreover, if you are allergic to tart cherry juice, it would be advisable to consult a doctor first.
Important Notice:
Tart Cherry Increases Antioxidant Capacity
The exact mechanisms underlying the health benefits of tart cherry use remain unknown. However, they seem to involve the potent antioxidant effects of this fruit. A 2019 report in Applied Physiology, Nutrition and Metabolism showed these effects in healthy men.
These researchers used a high-fat meal to trigger antioxidant defenses in the men. Participants received tart cherries during the meal. Compared to a placebo, eating the cherries increased the antioxidant capacity of the subjects. The cherries also lowered their triglycerides.
You can take advantage of these impressive antioxidant effects with a tart cherry supplement. A 2016 paper in the Journal of the International Society of Sports Nutrition shows you how. In this study, subjects took 480 milligrams of powdered tart cherry each day during the week before a half-marathon race. After the race, they had a better balance of free radical production and free radical elimination.
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Icipants Study Design And Intervention
This study was a 12-wk 2 × 2 crossover, randomized, placebo-controlled dietary intervention in overweight and obese participants . Individuals were recruited from the Phoenix, AZ, metropolitan area through the use of handbills, word-of-mouth notification, and poster displays as reviewed and approved by the Institutional Review Board at Arizona State University. Respondents were screened by telephone and onsite interviews at the metabolic kitchen at the Polytechnic campus at Arizona State University to assess general health height and weight were measured to determine BMI. Participants were aged 18 y, not pregnant, not diabetic, with no unresolved infections or diseases , and nonsmokers. Histories of medication and dietary supplement use were collected and those taking anti-inflammatory or lipid-lowering medications were excluded. This study was approved by the Institutional Review Board at Arizona State University and informed consent was obtained from each respondent prior to entering the study. This trial was registered at clinicaltrials.gov as NCT03636529.
Tart Cherry Can Help With Joint Pain Too
But its not just muscles that benefit. The anti-inflammatory properties of tart cherries can also be a blessing for people who struggle with joint pain, as is the case with inflammatory conditions like osteoarthritis.
One study found that consuming tart cherry juice twice a day for three weeks decreased inflammation by reducing levels of C-reactive protein, a marker of inflammation .
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How Can Tart Cherry Provide Relief
These nutrient-rich cherries help to reduce inflammation and oxidative stress in the body and may even help to offset the effect of gout on the bones and joints.
The anthocyanins of cherries seem to interfere with the internal oxidation process of energy production in the body.
They act as free radical scavengers and
Tart cherries also contain anti-inflammatory anthocyanins that can help to reduce uric acid levels in the body.
Reach for a bowl of fresh Montmorency cherries, a glass of sugar-free tart cherry juice, or a tart cherry supplement to stay on top of your symptoms.
Tart cherries are not just for good gout but also insomnia, muscle pain, and over-exertion, and they offer an excellent way to help the body recover.
They also have great potential for the treatment of diabetes, heart disease, and cancer.
For those seeking longevity and vital aging, tart cherries are highly recommended.
Plays An Important Role In The Functioning Of The Immune System
Melatonin is an essential part of the immune system as it helps in the production of white blood cells and the absorption of vitamin A and copper. Copper is necessary for maintaining white blood cells, and a deficiency could lead to more infectious diseases due to the bodys inability to fight off invaders. Tart cherry supplements provide the copper that the body needs for healthy brain functioning, iron absorption and maintaining a healthy thyroid .
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Tart Cherry May Help Improve Muscle Soreness And Reduce Inflammation
Have you ever done a tough workout at the gym and you wake up the next morning feeling like you cant move?
As it turns out, tart cherry could be good for helping relieve muscle pain and soreness, and get you back on your feet.
Why? Tart cherries are a concentrated source of phenolic compounds, which have antioxidant and anti-inflammatory activity that may help to protect muscles against damage and pain during strenuous exercise.
The Power Of Tart Cherries
For those suffering from gout, you may find relief with the power of tart cherries .
In fact, studies suggest that about 25% of people with gout use these and want to avoid problems with pharmaceuticals.
Tart cherries have been noted for their aid in alleviating symptoms of gout thanks to their rich antioxidant content and anti-inflammatory powers.
These small fruits help to alleviate inflammation, a key element of a gout attack.
One study of 633 patients with gout demonstrated that cherry intake is associated with a lower risk of gout attacks.
Scientists believe that part of the reason cherries might work is that they increase the excretion of urate and also limit the production of uric acid in the liver.
The abundant urate crystals in those with gout stimulate the production of pro-inflammatory cytokines.
Cherry counteracts this problem and also protects the body and joints by providing good antioxidant coverage.
This is an excellent non-pharmacological option for the treatment of many of the problems associated with gout.
Tart cherries have many phytochemicals that help, but cyanidin is the most prevalent compound.
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Alerna Uric Acid Support
Alerna Uric Acid Support is the best herbal supplement for gout. This supplement is a unique combination of antioxidants, vitamins and herbs. The main ingredients in it are tart cherry, turmeric and grape seed extract.
The ingredients are carefully chosen to support normal kidney functioning, joints and reduce uric acid levels. The vitamin B complex and vitamin C present in it support normal kidney functioning. The tart cherry, vitamin E and quercetin will help to normalize the uric acid levels. Whereas the turmeric, bromelain, and grape seed extract will support the joints.
Pros:
- Specially developed by kidney specialists.
- It is completely vegetarian friendly.
- Manufactured in the USA at a government inspected facility.
- The facility and quality are inspected by 3rd
Cons:
Can Cherry Juice Help With Gout Attack Or It Can Help Prevent Only
Cherry juice is an excellent supplement for providing gout relief and prevention. The combination of anthocyanins and vitamin C available in cherry juice gives the body relief from inflammation as well as prevents inflammation. Additionally, the vitamin C found in cherry juice can help make uric acid more soluble allowing it to be easily filtered out of your body.
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Uricel Uric Acid Support Formula
Are you looking out for a powerful uric acid supplement which helps to detox your body naturally? Then you have to purchase Uricel Uric Acid Support Formula.
It has 4 key ingredients turmeric, chanca piedra, celery seed extract and cherry extract. All these powerful antioxidants and anti-inflammatories are very helpful in treating the gout, reducing uric acid levels, soothing the pain and decreasing the swelling.
The chanca piedra is very effective in improving the digestive system so that it can successfully flush out the excess uric acid levels. And the most amazing part is that, instead of traditional capsules, this formula is available in liquid extracts.
Unlike the capsules, liquid extracts are more easily absorbed by the body within first 20 30 seconds. S, you will achieve effective results in a short period of time.
Pros:
- Formulated to supplement your daily diet.
- State of the art extraction and blending.
Cons:
Tart Cherry Decreases Chronicinflammation
Having chronic inflammation and oxidation from an unhealthy diet contributes to diabetes and obesity. Tart cherries feature many polyphenols, which decrease such processes, according to a 2016 paper in Antioxidants. This finding suggests that tart cherries might help fight these metabolic diseases. A 2018 report in Food and Function tested this hypothesis in overweight adults.
Subjects received 240 milliliters either tart cherry juice or a placebo each day for four weeks. After a two-week break, they switched to the opposite condition. Compared to a placebo, the tart cherry juice decreased the participants’erythrocyte sedimentation rate, ESR. People with diseases like arthritis often show an increased ESR suggesting that tart cherry might help manage inflammation in this disorder.
Tart cherry supplements also have a positive effect on inflammation in laboratory and animal models. A 2018 report in Nutrients showed that tart cherry extract decreased the inflammation caused by a high-fat diet in rats. These researchers also showed that the extracts decreased inflammation in cultured cells taken from these animals. Such findings suggest that taking tart cherry capsules can help you balance your diet.
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Cooking And Serving Tips
- Enjoy this hydrating and nutrient-packed smoothie for breakfast or a post-workout recovery snack.
- Look for tart cherry juice in the natural foods section of the grocery store. As the name suggests, the tart cherry juice is tart and flavorful, so it’s best combined with extra sweet pineapple to balance out the flavors.
- For optimal blending and an extra smooth consistency, add the liquid before the other ingredients, then blend for at least 90 seconds.
Measurement Of Serum Uric Acid
Archived plasma samples were thawed, warmed to 25°C, and aliquots combined with assay buffer, uric acid probe, and enzymatic reaction mix as part of a Uric Acid Assay kit and as directed by the manufacturer . Each master reaction mix was added to the wells of a 96-well microplate and incubated for 30 min at 37°C in the dark. Samples were then analyzed at 570 nm and quantified, with purified uric acid serving as an external standard. The CV was < 6.6%.
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Tart Cherry Decreases Musclesoreness
Doing an unusually hard workout will trigger symptoms of delayed-onset muscle soreness, DOMS. These symptoms can discourage people from working out, so scientists have sought potential remedies. The antioxidant properties of tart cherry products suggest that they might help treat DOMS. A 2016 article in the journal Nutrients tested this idea in soccer players.
Participants received a drink featuring 30 milliliters of tart cherry juice twice a day for eight days. During the testing period, the soccer players did a battery of intense exercises. This battery triggered symptoms of DOMS in a placebo condition. Drinking the tart cherry juice attenuated these symptoms.
Tart cherry capsules also decrease post-exercise pain, according to a 2015 report in the Journal of the International Society of Sports Nutrition. These researchers gave healthy men a capsule featuring 480 milligrams of tart cherry powder for seven days before, and two days after, resistance exercise training. Compared to a placebo, this treatment decreased subjective feelings of muscle soreness and biochemical markers of muscle damage.
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Analysis And Calculation Of Insulin Sensitivity And Resistance
Insulin sensitivity and resistance were calculated through the use of a panel of indirect indices including the following: 1) the HOMA index, calculated as glucose × insulin /22.5 2) the quantitative insulin-sensitivity check index , calculated as 1/ and 3) the McAuley index, calculated as exp. The glucose/insulin ratio and 1/insulin reciprocal were also calculated.
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How Cherries May Help Prevent Gout
Scientists know that cherries contain high levels of antioxidants, including anthocyanins and quercetin, as well as other nutrients. It is unclear how these nutrients may work individually or together to lower urate levels and decreases the chance of a gout attack.
Some researchers2 theorize that cherries:
- Have anti-inflammatory properties that may reduce the painful inflammation related to gout attacks
- May help counteract the process that leads to changes in bones in gout-affected joints
- Reduce oxidative stress , which is associated with gout
Experts suspect that oxidative stress in the body begins a biochemical cascade that promotes inflammation, which over time leads to gout and other degenerative diseases.
More researchparticularly large studies involving human subjectsis needed to find out exactly if and how cherries prevent gout attacks.
See Gout Prevention
Properties And Health Benefits
Tart cherry juice contains anthocyanins, which are anti-inflammatory compounds responsible for the red, orange, blue, and purple colors of fruits and vegetables. This substance may help to combat some chronic inflammatory diseases, including arthritis, diabetes, cardiovascular disease, and cancer. Many medications used to treat arthritis target inflammation as a way to reduce symptoms and improve quality of life.
Tart cherry juice also has high concentrations of other polyphenols, including flavonoids. All of these nutritional compounds make tart cherry juice a potent antioxidant and anti-inflammatory food and potential adjunct therapy for people with arthritis and gout.
The process by which anthocyanins help decrease inflammation may be by suppressing pro-inflammatory compounds in the body, such as cyclooxygenase, or COX. By this and other unknown mechanisms, tart cherry juice may help reduce pain and stiffness associated with arthritis and other related joint pain disorders.
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Tart Chery Juice Vs Tart Cherry Capsules
Interestingly enough, studies dont indicate one being more beneficial than the other.
The vast majority of studies done on tart cherry use juice and show positive results. But ones that are done using powder show very similar outcomes.
Powderswhat you find in tart cherry capsulesare derived from the skins of tart cherries and provide similar benefits to those found from tart cherry juice .
Another study using the same dosage even found that inflammatory markers decreased by a whopping 47% in groups who supplemented with tart cherry powder !
Hows that for a bang for your buck…
A Guide To Tart Cherry Concentrate Supplements
by H& PC Team | Nov 18, 2021 | Blog |
If youve never heard of tart cherries, theyre simply just another variety of cherry. As the name suggests, this bright red beauty is more on the tangy side in comparison to your usual summer cherry. Theyre also commonly known as sour cherries, Montmorency cherries, or dwarf cherries.
Tart cherry supplements extract the goodness from these cherries and package it up in a variety of convenient forms. A browse online will show you that tart cherry supplements are sold as a juice, as a concentrate , a powder, and even in capsules. You can also find tart cherries as a frozen or dried fruit in specialty supermarkets or health food stores. Take your pick, but remember with juices to always opt for the unsweetened varieties!
Tart cherries pack a nutritional punch they contain vitamin A, vitamin C, iron, magnesium, manganese, potassium, copper and vitamin K. Theyre also particularly alluring for their high levels of antioxidants, namely cyanidin, and are ranked within the top 50 highest antioxidant-containing foods. Snaps for tart cherries!
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How Does Cherry Juice Treat Gout
Cherry juice treats gout flare-ups by reducing the level of uric acid in the body. Since uric acid buildup is what causes gout, it only goes to reason that cherry juice could prevent or treat gout flare-ups.
A 2011 study noted that 100 percent tart cherry juice significantly reduced the level of serum uric acid levels in participants who drank 8 ounces of the juice every day for four weeks.
Its not only cherry juice that could lower uric acid levels cherry juice concentrate can also be beneficial for those with gout.
A 2012 pilot study found that consuming cherry juice concentrate lowered the levels of uric acid in the body. One portion of the study demonstrated that cherry extract was more effective than pomegranate concentrate at lowering uric acid levels.
A retrospective portion of the study found that when consumed for a four-month period or longer, cherry juice concentrate reduced gout flare-ups significantly.
An online survey directed at people with gout also suggested cherry intake can improve symptoms. Of the survey respondents, 43 percent said that they used cherry extract or juice to treat their gout symptoms. The survey found that those who used cherry supplements reported significantly fewer flare-ups.
Of course, this study is limited because it relies on the subjects to report their own symptoms. Even so, the results are promising.
Your Good Health: Gout Kept In Check With Tart Cherries
Dear Dr. Roach: I got a call from my internist that my blood test showed an elevated uric acid and I would need to start allopurinol for gout. I had been having big-toe pain at night. A nurse friend gave me some of her tart cherry extract pills to take until I started medication. Before picking up the medication, I read online about people who had affirmed time and time again that taking tart cherry, in almost any form, relieved their gout pain. I decided to continue it to see how long the relief would last.
That was three years ago, and I have not needed the allopurinol nor had to worry about the side- effects that can accompany it. I do not take the tart cherry pills/capsules daily, only when twinges start. Sometimes I just keep tart cherry juice or the canned cherries themselves on hand. Much easier, and cheaper as well. It might not work for everyone, but it certainly was worth a try! I am yet another affirmation of at least trying an alternative.
P.B.
Im glad it worked for you, and it gives me a chance to talk about the difference between gout and having high uric acid levels.
Gout has been known since ancient times. The word gout comes from the Latin gutta, meaning drop. It reflects the theory of humours, which was what was thought to cause the disease. Actually, it is caused by the deposition of uric acid crystals into a joint, usually a single joint such as the big toe, where it has the lovely, old-fashioned name podagra.
R.W.
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